CRISPR/Cas9 ADCY7 knockout stimulates the insulin secretion pathway leading to excessive insulin secretion
نویسندگان
چکیده
Brief Summary: This is a single case report describing possible new candidate gene (ADCY7) for congenital hyperinsulinism. Mutations in the ADCY7 may be cause of hyperinsulinism but more cases are needed and molecular mechanisms studied detail.
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ژورنال
عنوان ژورنال: Yearbook of pediatric endocrinology
سال: 2022
ISSN: ['1662-3991', '1662-4009']
DOI: https://doi.org/10.1530/ey.19.2.8